Retinal nerve fiber layer thinning in Parkinson disease

The Retinal Nerve Fiber Layer Thickness is Related to Severity of Parkinson’s Disease

Introduction: We investigated correlation between the retinal nerve fiber layer (RNFL) thickness and the severity of Parkinson's disease (PD). Methods: In this study, the RNFL thickness of 23 patients with Parkinson’s disease (PD) was compared to normal controls (NCs). PD severity was assessed by the MDS-UPDRS (movement disorder society Unified Parkinson Disea...

Inner retinal layer thinning in Parkinson disease.

OBJECTIVE To quantify retinal thickness in patients with Parkinson disease (PD). METHODS Forty-five eyes of 24 PD patients and 31 eyes of 17 control subjects underwent a comprehensive ophthalmologic examination. We used optical coherence tomography to examine retinal thickness, separately quantifying the inner and outer retinal layers. Intraocular pressure was measured by Goldmann applanation...

Optical Coherence Tomography Based Evaluation of Retinal Changes in Parkinson’s Disease

Introduction: Optical coherence tomography (OCT) is a non-invasive imaging technique routinely used to visualize and quantify the layers of the retina. Originally developed for retinal diseases and glaucoma, optical coherence tomography (OCT) allows direct visualization and measurement of the optic nerve head topography and of retinal nerve fibre layer (RNFL) thickness with micron-scale resolut...

Retinal Nerve Fibre Layer Thinning in Alzheimer Disease

Schizophrenia and the eye

Although visual processing impairments are common in schizophrenia, it is not clear to what extent these originate in the eye vs. the brain. This review highlights potential contributions, from the retina and other structures of the eye, tovisual processing impairments in schizophrenia and high-risk states. A second goal is to evaluate the status of retinal abnormalities as biomarkers for schiz...